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目的:分析绝经前后子宫内膜腺癌的发病相关因素、临床表现、病理组织特点、手术分期等,为需要保留生育功能年轻女性采取不同的治疗方案提供参考依据。方法:根据是否绝经将65例子宫内膜腺癌患者临床资料分为两组进行回顾性分析,未绝经组21例,绝经组44例。结果:未绝经组和绝经组比较,临床表现、发病相关因素高血压和糖尿病有统计学意义(P<0.05)。组织病理学分级有统计学意义(P<0.05)。其余临床资料无统计学差异(P>0.05)。结论:绝经前的子宫内膜癌患者其发病相关因素较绝经后少,组织分化程度高。因此,早发现、早诊断、早治疗子宫内膜癌患者可以提高其生存率,年轻子宫内膜癌患者其分化程度高Ia期者可考虑保留生育功能。
OBJECTIVE: To analyze the related factors, clinical manifestations, histopathological features and staging of endometrial adenocarcinoma before and after menopause so as to provide reference for different treatment options for young women who need to retain fertility. Methods: According to whether the clinical data of 65 cases of endometrial adenocarcinoma were divided into two groups according to whether they were menopause or not, 21 cases of non-menopause group and 44 cases of menopause group were retrospectively analyzed. Results: Compared with menopause group, the clinical manifestations, morbidity-related factors of hypertension and diabetes were statistically significant (P <0.05). Histopathological grading was statistically significant (P <0.05). The remaining clinical data was not statistically different (P> 0.05). Conclusion: The incidence of premenopausal endometrial cancer related factors less postmenopausal, high degree of tissue differentiation. Therefore, early detection, early diagnosis and early treatment of endometrial cancer patients can increase their survival rate, young endometrial cancer patients with high degree of differentiation of Ia may consider retaining reproductive function.