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目的:分析颌骨中心性腺源性肿瘤的临床特点、治疗方法以及预后相关因素,提高此类疾病的诊断水平和治疗效果。方法:收集四川大学华西口腔医院1986—2006年间收治的22例颌骨中心性腺源性肿瘤的临床及随访资料并进行分析。结果:22例颌骨中心性腺源性肿瘤,男7例,女15例;上颌骨9例,下颌骨13例。29~59岁病例占68.2%。临床表现不典型,以颌骨膨隆或肿块、疼痛、牙松动较为多见。诊断困难,病理学类型多样,恶性占绝大多数,黏液表皮样癌最为常见,占45.5%。手术是主要的治疗方式,预后与其病理学类型和临床分期密切相关。结论:术前活检是颌骨中心性腺源性肿瘤的确诊手段。手术是主要的治疗方式,手术方式主要是根治性切除,根据具体情况选择区域颈淋巴清扫术。足够边界的切除是减少肿瘤复发的关键。
OBJECTIVE: To analyze the clinical features, treatment and prognostic factors of central gland tumor of the jaw, and to improve the diagnostic level and therapeutic effect of these diseases. Methods: The clinical data and follow-up data of 22 cases of central gland tumor of the gonad from 1986 to 2006 in West China Stomatology Hospital of Sichuan University were collected and analyzed. Results: Twenty-two cases of central gland tumor of jaw were found in 7 males and 15 females, 9 cases of maxilla and 13 cases of mandible. 29 to 59 years old accounted for 68.2% of cases. Clinical manifestations of atypical to jaw swelling or mass, pain, loose teeth more common. Diagnosis is difficult, the pathological type is diverse, the vast majority of malignant, mucinous epidermoid carcinoma is the most common, accounting for 45.5%. Surgery is the main treatment, prognosis and its pathological type and clinical stage are closely related. Conclusion: Preoperative biopsy is the diagnosis of central gland tumor of the jaw. Surgery is the main treatment, the main surgical approach is radical resection, according to the specific circumstances of regional neck dissection. Excision of sufficient boundaries is the key to reducing tumor recurrence.