论文部分内容阅读
（±）－顺式－１－苄基－３－甲基－４－苯胺基哌啶（ｃｉｓ－１）是合成手性强效镇痛剂羟甲芬太尼（ｏｈｍｅｆｅｎｔａｎｙｌ）类化合物的重要中间体。Ｎ－苄基－３－甲基－４－苯亚胺基哌啶（３）经ＫＢＨ４还原得到（±）－顺，反－１－苄基－３－甲基－４－苯胺基哌...
(±) -cis-1-Benzyl-3-methyl-4-anilinopiperidine (cis-1) is an important intermediate for the synthesis of the chiral potent analgesic, ohmefentanyl body. Reduction of (±) -cis-, trans-1 -benzyl-3-methyl-4-anilino piperidine by KBH4 reduction of N-benzyl-3-methyl-4-phenylaminopiperidine (3) .