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目的了解2010-2014年厦门市居民食管癌的疾病负担,为厦门市食管癌防治工作提供科学依据。方法利用厦门市死因监测系统收集2010-2014年厦门市居民食管癌死亡数据,运用伤残调整寿命年(DALY)对食管癌疾病负担进行测算,用SAS 9.2软件对相关数据进行统计分析。结果 2010-2014年厦门市居民食管癌共死亡2 045例,死亡率为21.35/10万,标化死亡率为21.83/10万。男性食管癌死亡率为32.79/10万,标化死亡率为34.05/10万;女性食管癌死亡率为9.99/10万,标化死亡率为9.96/10万。居民每千人口食管癌早死所致的健康生命损失年(YLL)、残疾所致的健康生命损失年(YLD)和DALY分别为1.607、0.011和1.618年。30岁以上人群YLL、YLD和DALY男性均高于女性,50~69岁人群负担最重。结论 YLL是厦门市居民食管癌疾病负担的主要来源;30岁以上男性以及50~69岁老年群体是食管癌防治的重点人群。
Objective To understand the disease burden of esophageal cancer in Xiamen City from 2010 to 2014 and to provide scientific evidence for the prevention and treatment of esophageal cancer in Xiamen City. Methods The data of death from esophageal cancer in Xiamen residents from 2010 to 2014 were collected using the death cause monitoring system in Xiamen City. The disability-adjusted life span (DALY) was used to estimate the burden of esophageal cancer. SAS 9.2 software was used to analyze the data. Results A total of 2 045 esophageal cancer deaths occurred in Xiamen City from 2010 to 2014, with a mortality rate of 21.35 / 100 000 and a standardized mortality rate of 21.83 / 100 000. Male esophageal cancer mortality was 32.79 / 100000, the standardization mortality was 34.05 / 100000; female esophageal cancer mortality was 9.99 / 100000, the standardization of death was 9.96 / 100000. The number of years of healthy loss of life (YLL) due to premature death of esophageal cancer per 1,000 population, the years of healthful loss of life (YLD) and DALY due to disability were 1.607, 0.011 and 1. 618 years, respectively. YLL, YLD and DALY males over 30 years old were higher than females, and those aged 50-69 had the heaviest burden. Conclusion YLL is the main source of disease burden of esophageal cancer in Xiamen. Over 30-year-old men and 50-69-year-olds are the key population for the prevention and treatment of esophageal cancer.