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本文报道了密执安大学医疗中心22年期间治疗的10例鼻咽癌患者,年龄7~16岁,平均13.5岁。男性8例,女性2例。所有患者均行鼻咽部活检并经组织学证实。随访期为5年以上。从症状发作到就诊时间为2~15月。最常见主诉为颈部包块和听力丧失,其中5例病人表现为渗出性或化脓性中耳炎。8例于初诊时存在颈部转移。4例表现有脑神经损害,最常损害第Ⅴ、Ⅵ和Ⅲ神经。所有患者均行颅底X线照相,4例发现有颅底骨质破坏。所有患者均按TNM分类法进行分类。通过四“T”期描述了原发肿瘤范围和大小。从T 1s及T2s表明肿瘤限于鼻咽部。超过鼻咽部为T3。当
This article reports 10 cases of nasopharyngeal carcinoma treated by the University of Michigan Medical Center during the 22 years, aged 7 to 16 years, with an average of 13.5 years. There were 8 males and 2 females. All patients underwent nasopharyngeal biopsy and histological confirmation. Follow-up period is more than 5 years. From the onset of symptoms to treatment time is from 2 to 15 months. The most common complaints were neck mass and hearing loss, of which 5 patients showed exudative or suppurative otitis media. Eight cases had neck metastasis at the time of initial diagnosis. In 4 cases, there was brain nerve damage, which most often damaged the nerves of the V, VI, and III. Skull base radiographs were performed in all patients, and skull base bone destruction was found in 4 cases. All patients were classified according to the TNM classification. The primary tumor range and size were described by four “T” phases. From T 1s and T2s, the tumor was limited to the nasopharynx. More than T3 for the nasopharynx. when