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Tumor growth and metastasis are angiogenesis-dependent.Anti-angiogenic therapy may be a useful approachto cancer therapy.This review discussed tumor angiogenesis and immunotherapy of targeting tumorangiogenesis from two main aspects:(1)active vaccination to induce effective anti-angiogenesis immunity;(2)passive immunotherapy with anti-pro-angiogenic molecules relevant antibody.Evidence from the recent yearssuggested that anti-angiogenic therapy should be one of the most promising approaches to cancer therapy.Cellular & Molecular Immunology.2004;1(3):161-166.
Tumor growth and metastasis are angiogenesis-dependent. Anti-angiogenic therapy may be a useful approach to cancer therapy. This review discusses tumor angiogenesis and immunotherapy of targeting tumorangiogenesis from two major aspects: (1) active vaccination to induce effective anti-angiogenesis immunity; ( 2) passive immunotherapy with anti-pro-angiogenic molecules relevant antibody. Evidence from the recent years that the anti-angiogenic therapy should be one of the most promising approaches to cancer therapy. Cellular & Molecular Immunology. 2004; 1 (3) 166.