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目的:分析雷贝拉唑联合克拉霉素阿莫西林治疗胃溃疡临床疗效。方法:选取2014年3月~2015年3月间收治的胃溃疡患者76例作为研究对象,根据治疗方式不同随机分为观察组及对照组各38例。对比两组患者的临床疗效及血清炎症因子水平差异。结果:观察组患者接受治疗后的治愈率高于对照组,无效率低于对照组患者(P<0.05);血清CRP、IL-6、TNF-α水平低于对照组,IL-2水平高于对照组患者(P<0.05)。结论:胃溃疡患者接受雷贝拉唑联合克拉霉素阿莫西林治疗,可以提升治疗效果,降低全身炎症反应。
Objective: To analyze the clinical efficacy of rabeprazole combined with clarithromycin amoxicillin in the treatment of gastric ulcer. Methods: A total of 76 gastric ulcer patients who were admitted to our hospital from March 2014 to March 2015 were selected as study subjects and randomly divided into observation group (38 cases) and control group (38 cases) according to different treatment methods. The clinical efficacy and serum levels of inflammatory cytokines were compared between the two groups. Results: The cure rate of observation group was higher than that of control group, the inefficiency was lower than that of control group (P <0.05), the level of serum CRP, IL-6 and TNF-α were lower than that of control group In control group (P <0.05). Conclusion: Patients with gastric ulcer treated with rabeprazole combined with clarithromycin amoxicillin can improve the therapeutic effect and reduce the systemic inflammatory response.