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本文作者于1963～1980年对123例非肝外胆道梗阻或动脉肝性发育不良的新生儿肝病作了6～18年的随访研究。结果73例特发性新生儿肝炎死于肝功衰竭者18%,败血症者6%,伴发缺陷者14%;25%在一岁以内死亡,一岁以后死亡9%。存活的非家族性特发性新生儿肝炎40例中有3例进展为慢性肝病,其余已无肝病证据或仅有轻度肝功异常。9例家族性特发性新生儿肝炎预后较差,其中6例死亡。21例巨细胞病毒肝炎肝损害较轻,仅2例一岁以后分别死于肝功衰竭及肺炎,但脑损害极严重,存活的16例中3例有轻～中度、4例有重度后遗症,没有发生慢性肝病
The authors conducted a follow-up study of 123 cases of neonatal liver disease with non-extrahepatic biliary obstruction or arterial hepatic dysplasia from 1963 to 1980. Results 73 cases of idiopathic neonatal hepatitis died of liver failure, 18%, 6% of sepsis, 14% of patients with concomitant defects; 25% died within one year old, 9% died after one year old. Three of the 40 survivors of non-familial idiopathic neohepatitis progressed to chronic liver disease, with no evidence of liver disease or only mild liver dysfunction. Nine patients with familial idiopathic neonatal hepatitis had a poor prognosis, of which 6 died. 21 cases of cytomegalovirus hepatitis liver damage lighter, only 2 cases died of liver failure and pneumonia after the first year of life, but the brain damage is very serious, survival in 16 cases, 3 cases were mild to moderate in 4 cases with severe sequelae No chronic liver disease occurred