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目的探讨奥美拉唑、多潘立酮联合替普瑞酮治疗反流性食管炎的疗效。方法 175例反流性食管炎患者分成对照组和观察组,对照组87例给予奥美拉唑、多潘立酮治疗,观察组88例在对照组基础上加用替普瑞酮,观察疗效和不良反应。结果观察组总有效率92.0%,明显优于对照组的67.8%(P<0.05)。观察组治疗后症状积分明显低于对照组(P<0.05),不良反应低。结论奥美拉唑、多潘立酮联合替普瑞酮治疗反流性食管炎,可显著提高临床疗效,副作用少。
Objective To investigate the curative effect of omeprazole, domperidone and teprenone on reflux esophagitis. Methods A total of 175 patients with reflux esophagitis were divided into control group and observation group. 87 patients in the control group were treated with omeprazole and domperidone, and 88 patients in the observation group were treated with teprenone on the basis of the control group. The efficacy and adverse reactions . Results The total effective rate was 92.0% in the observation group, which was significantly better than 67.8% in the control group (P <0.05). Symptoms after treatment in the observation group was significantly lower than the control group (P <0.05), adverse reactions. Conclusion Omeprazole and domperidone combined with teprenone in the treatment of reflux esophagitis can significantly improve the clinical curative effect with few side effects.