论文部分内容阅读
目的探讨老年高血压晨峰与尿微量白蛋白(MAU)的关系。方法对入选的90例老年高血压患者行24h动态血压监测,根据监测结果分为晨峰组(n=44)、非晨峰组(n=46),所有对象血压监测次日行晨MAU、血糖及肾功能检测,观察两组间差别。结果晨峰组24h、白昼、夜间平均收缩压高于非晨峰组(P<0.05),两组的24h、白昼、夜间平均舒张压差异无统计学意义(P>0.05)。晨峰组MAU、尿酸与非晨峰组比较差异均有统计学意义(P<0.05),两组的尿素氮、肌酐比较,差异无统计学意义(P>0.05)。MAU与收缩压晨峰、血糖、尿酸呈中度相关,与年龄、舒张压晨峰呈低度相关,与尿素氮、肌酐无相关性。结论老年高血压晨峰与MAU有关,临床工作中应重视血压晨峰的控制。
Objective To investigate the relationship between morning peak of hypertension and urine microalbumin (MAU). Methods Ninety elderly hypertensive patients were selected for ambulatory blood pressure monitoring in 24 hours. According to the monitoring results, they were divided into morning peak group (n = 44) and non-morning peak group (n = 46) Blood glucose and renal function tests were observed differences between the two groups. Results The average systolic blood pressure of morning peak group at 24h, day and night was higher than that of non-morning peak group (P <0.05). There was no significant difference in 24h, daytime and nighttime diastolic pressure between two groups (P> 0.05). There were significant differences in MAU, uric acid and non-morning peak group between the morning peak group and the non-morning peak group (P <0.05). There was no significant difference between the two groups in urea nitrogen and creatinine (P> 0.05). MAU systolic blood pressure morning peak, blood glucose, uric acid were moderately correlated, and age, diastolic blood pressure was a low correlation peak, and urea nitrogen, creatinine no correlation. Conclusions The morning peak of senile hypertension is related to MAU. The clinical work should pay attention to the control of blood pressure morning peak.