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作者研究了67例住院成年结核病患者。入院时每例均测定血清和尿溶菌酶,测定法系采用以卵白溶菌酶作标准的比浊法。其对照值限为7~14微克/毫升。 67例中计轻型19例(28%),中型29例(43%)及重型19例(28%)。痰涂片或培养结核杆菌阳性者55例(82%),痰阴性而备具有活动性结核有力的临床证据者12例(18%)。测定结果血清溶菌酶含量与种族、性别及70岁以下的年龄无关。70岁以下者,平均血清溶菌酶均在11.3~14.5微克/毫升。但71岁以上的血清溶菌酶的平均值显较年轻组为高(21.1~23微克/毫升)。阳性痰与血清溶菌酶活性的增加似有关联。痰检阳性的55例中,21例(38%)的血清溶菌酶活性增
The authors studied 67 hospitalized adults with tuberculosis. Serum and urine lysozyme were measured in each case on admission, and the assay was performed using the turbidimetric method using egg white lysozyme as a standard. The control value of 7 to 14 micrograms / milliliter. Among 67 cases, 19 (28%) were mild, 29 (43%) were medium, and 19 (28%) were heavy. Fifty-five (82%) patients were sputum smear-positive or Mycobacterium tuberculosis-positive and 12 (18%) had sputum-negative clinical evidence of active tuberculosis. Determination of serum lysozyme content and race, sex and age of 70 years of age has nothing to do. Under 70 years of age, the average serum lysozyme were 11.3 to 14.5 micrograms / ml. However, mean serum lysozyme over 71 years of age was significantly higher (21.1-23 μg / mL) in the younger group. Positive sputum and serum lysozyme activity seems to be related. Of the 55 sputum positive tests, 21 (38%) had increased serum lysozyme activity