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目的探讨经单鼻孔入路垂体腺瘤切除手术、术后并发症及死亡原因。方法对136例垂体瘤患者行单鼻孔入路垂体腺瘤切除术并分析其疗效、术后并发症及死亡原因。结果肿瘤全切89例(65.4%),次全切除46例(33.8%),因术中大出血未行手术切除1例。术后出现并发症16例(11.8%),死亡4例(2.9%)。结论单鼻孔入路切除垂体腺瘤有手术时间短,创伤小,并发症少等优点。但仍有诸多因素可导致术后并发症甚至死亡,因此我们必须做好术前评估,选择合适的手术适应症,进行个体化手术设计,掌握局部显微解剖,娴熟手术技巧,严密术后观察。
Objective To investigate the surgical treatment of pituitary adenoma by single nostril approach, postoperative complications and causes of death. Methods One hundred and sixty - six patients with pituitary adenoma underwent resection of the pituitary adenoma by single nostril and analyzed its curative effect, postoperative complications and causes of death. Results Tumor resection in 89 cases (65.4%), subtotal resection in 46 cases (33.8%), due to intraoperative bleeding without surgery in 1 case. Postoperative complications occurred in 16 cases (11.8%), 4 patients died (2.9%). Conclusions Single nostril resection of pituitary adenoma has the advantages of short operation time, less trauma and less complications. However, there are still many factors that may lead to postoperative complications or even death. Therefore, we must make preoperative evaluation, select appropriate surgical indications, design individualized surgery, master microdissection, skilled surgical techniques and strict postoperative observation .