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目的观察卡舒宁联合流感疫苗对老年性慢性支气管炎合并急性感染的防治效果。方法选择多年反复感染、咳嗽、咳痰、不同程度哮喘的老年慢性支气管炎患者138人,随机分为观察组73人,对照组65人。观察组接种流感疫苗后2周注射卡舒宁,每周2次,疗程3个月;对照组仅注射卡舒宁,方法同观察组。1年后,对两组病例统一进行电话或入户随访,内容包括慢性支气管炎急性感染次数、急性感染时住院次数及急性感染时抗生素治疗疗程。结果观察组患者慢性支气管炎急性感染次数和住院总次数明显减少,抗生素治疗疗程明显缩短,与对照组相比,差异均有统计学意义(P<0.01)。结论卡舒宁联合流感疫苗可明显提高老年性慢性支气管炎合并急性感染的防治效果。
Objective To observe the prevention and treatment effect of Kasudin combined with influenza vaccine on senile chronic bronchitis complicated with acute infection. Methods Thirty-eight elderly patients with chronic bronchitis who were repeatedly infected, cough, expectorant and asthmatic were randomly divided into observation group (73 cases) and control group (65 cases). Observation group vaccinated with flu 2 weeks after the injection of card Shu Ning, 2 times a week, the course of treatment for 3 months; control group only injected with Kasushining, the same method with the observation group. A year later, the two groups of patients unified telephone or home visit, including the number of acute exacerbations of chronic bronchitis, the number of hospitalizations during acute infection and antibiotic treatment of acute infection. Results In the observation group, the number of chronic bronchitis and the total number of hospitalizations were significantly reduced, and the course of antibiotic treatment was significantly shortened. Compared with the control group, the differences were statistically significant (P <0.01). Conclusions Casudin combined with influenza vaccine can significantly improve the prevention and treatment of senile chronic bronchitis complicated with acute infection.