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血管内皮分布在血管组织和循环血液的界面上,占据很大的表面积.成年男性的内皮细胞(EC)总体积与肝脏差不多,重约1.5-2.0kg.动脉、静脉及毛细血管的EC在形态学、超微结构及生化方面均有差异,而其共同的特点是面积体积比(面积/体积)大,代谢旺盛,EC表面持续暴露于循环血液,构成复杂.血管EC通过细胞间紧密连接形成高度有序的单层结构,这些EC的基础更新率很低.这种单层结构的连续性对于血管壁行使正常功能十分关
The vascular endothelium distributes at the interface between vascular tissue and circulating blood and occupies a large surface area.The total volume of endothelial cells (ECs) in adult men is about the same as that of the liver, weighing about 1.5-2.0 kg.The ECs of arteries, veins and capillaries are similar in morphology There are differences in the study, ultrastructure and biochemistry, and its common feature is the large area to volume ratio (area / volume), strong metabolism, continuous exposure of the EC surface to the circulating blood to form a complex vascular EC formed by tight junctions between cells Highly ordered single-layer structure, the basis of these EC update rate is very low. The continuity of this single-layer structure for the normal function of the vessel wall is very close