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２０例巨大垂体腺瘤经额－－硬膜下入路对肿瘤行显微膜外解剖，游离探查结合膜下分次切除，反复交替达到肿瘤连包膜全切除。施行该术式时应善于使用显微镜，分离鞍隔与瘤体时，勿伤漏斗部和正常垂体，保护好视神经滋养血管，以免术后合并症的出现．结果：除２例术前全失明外，余１８例视力、视野全部得到改善；１８例术前内分泌异常者１２例恢复正常；随访一年余无复发和死亡病例。
Twenty cases of giant pituitary adenomas underwent microdissection outside the tumor through the subfrontal subdural approach. Free probing was performed in combination with subtocolumn excision and repeated resections were performed to achieve total resection of the tumor. When performing this procedure, you should be good at using the microscope. When separating the saddle septum from the tumor, do not injure the infundibular part and the normal pituitary, and protect the optic nerve to nourish blood vessels to prevent the occurrence of postoperative complications. Results: In addition to 2 cases of blindness before surgery, the remaining 18 cases of vision and vision were all improved; 18 cases of preoperative abnormal endocrine abnormalities in 12 cases returned to normal; follow-up more than a year without recurrence and deaths.