论文部分内容阅读
目的:研究并讨论口服降糖药联合注射液甘精胰岛素对2型糖尿病治疗中的疗效。方法:在2009年2月~2011年2月我院收治的2型糖尿病患者中抽取40例,40例患者均口服降糖药及饮食控制但血糖均得不到有效控制。40例患者每天均进行1次的甘精胰岛素注射液注射。观察并记录患者在治疗前后的糖化血清蛋白、空腹C肽、空腹血糖和餐后2h的血糖的变化。结果:治疗前后,患者的空腹C肽未出现明显变化;但治疗后患者的糖化血清蛋白、空腹血糖和餐后2h的血糖均比治疗前显著下降,其差异在统计学上有意义(P<0.05)。结论:口服降糖药联合注射液甘精胰岛素对控制2型糖尿病的临床疗效好,安全性高,值得推广使用。
Objective: To study and discuss the efficacy of oral hypoglycemic agents combined with glargine in the treatment of type 2 diabetes mellitus. Methods: Forty patients with type 2 diabetes admitted to our hospital from February 2009 to February 2011 were enrolled. Forty patients underwent oral hypoglycemic agents and diet control but their blood glucose levels were not effectively controlled. Forty patients were injected with glargine injection once a day. The change of glycosylated serum protein, fasting C-peptide, fasting blood glucose and blood sugar of patients before and after treatment were observed and recorded. Results: Before and after treatment, there was no significant change of fasting C-peptide in patients. However, after treatment, the glycosylated serum protein, fasting blood glucose and postprandial blood glucose of 2h were significantly lower than those before treatment, the difference was statistically significant (P < 0.05). Conclusion: Oral hypoglycemic agents in combination with injection of glargine on the prevention and treatment of type 2 diabetes, good clinical efficacy, high safety, it is worth promoting the use of.