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目的探讨含酚炉甘石洗剂的制备、质量控制及其治疗皮肤炎性疾病的临床疗效。方法选择安化县人民医院2014年4月—2016年3月收治的皮肤炎性疾病患者500例,随机分为对照组240例和治疗组260例。对照组患者给予炉甘石洗剂,治疗组患者给予含酚炉甘石洗剂局部外用。比较两组患者的临床疗效及不良反应发生情况。结果治疗组患者临床疗效优于对照组(P<0.05)。两组患者治疗期间均未见严重不良反应发生。结论含酚炉甘石洗剂制备简单可行,质量稳定可控,且其治疗皮肤炎性疾病的临床疗效确切,且安全性好。
Objective To investigate the preparation and quality control of calamine-containing lotion and its clinical efficacy in the treatment of skin inflammatory diseases. Methods A total of 500 patients with dermal inflammatory diseases admitted to Anhua People’s Hospital from April 2014 to March 2016 were randomly divided into control group (240 cases) and treatment group (260 cases). Patients in the control group were treated with calamine lotion, and the patients in the treatment group were topically treated with cellar lotion containing phenol. The clinical efficacy and adverse reactions of the two groups were compared. Results The clinical efficacy of the treatment group was better than that of the control group (P <0.05). No serious adverse reactions occurred in both groups during treatment. Conclusion The preparation of phenol-containing calamine lotion is simple and feasible, the quality is stable and controllable, and its curative effect on dermatitis is definite and safe.