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以结核菌素纯蛋白衍生物(PPD)为丝裂源作淋巴细胞转化试验,检测结核性(17例)和非结核性(14例)胸膜炎患者的外周血淋巴细胞(PBL)和胸腔积液淋巴细胞(PEL)对PPD 的反应性。结果显示:结核性胸膜炎患者无论PPD 皮试是阳性还是阴性,其PEL 的PPD 刺激指数(PPD-SI)都显著高于PBL(P 分别<0.001与<0.01);结核性PEL 的PPD-SI 显著高于非结核性PEL(P<0.001)。提示PPD 胸腔积液淋巴细胞转化试验可作为诊断结核性胸膜炎的有效方法。
Lymphocyte transformation test was performed with PPD as mitotic source. Peripheral blood lymphocytes (PBLs) and pleural effusion (PBL) were detected in patients with tuberculous (17 cases) and non-tuberculous (14 cases) Reactivity of lymphocytes (PEL) to PPD. The results showed that the PPD-SI of PEL was significantly higher than that of PBL (P <0.001 and <0.01, respectively), no matter whether PPD skin test was positive or negative, the PPD-SI of tuberculous PEL was significant Higher than non-tuberculous PEL (P <0.001). Tip PPD pleural effusion lymphocyte transformation test can be used as an effective diagnosis of tuberculous pleurisy.