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The target compound 1,2,4-triazole Schiff base containing pyrazole ring was synthesized by 4-amino-2,4-dihydro-5-((3,5-dimethyl- lH-pyrazol-1-yl)methyl)-3H-1,2,4-triazole-3-thione and 3,4,5-trimethoxy benzaldehyde.The structure was confirmed by IR,~1H NMR,H RMS,elemental analysis and single-crystal X-ray diffraction.The crystal belongs to the triclinic system,space group P1 with a = 7.8772(17),b = 8.2986(18),c = 15.392(3) A,α= 93.360(4),β= 94.609(4),γ= 93.584(4)°,C_(18)H_(22)N_6O_3S,M_r= 402.47,V= 998.9(4) A~3,Z= 2,F(000) = 422,D_c =1.335 g/cm~3,μ= 0.194 mm~(-1),the final R = 0.0533 and wR = 0.1329 for 3517 observed reflections with I> 2σ(I).The preliminary bioassay results indicate that the target compound has good fungicidal activity against Gibberlla nicotiancola in EC50 value and F.O.f.sp.niveum in EC_(95) value.
The target compound 1,2,4-triazole Schiff base containing pyrazole ring was synthesized by 4-amino-2,4-dihydro-5- (3,5-dimethyl- lH-pyrazol-1-yl) -1,2,4-triazole-3-thione and 3,4,5-trimethoxy benzaldehyde. The structure was confirmed by IR, ~ 1H NMR, H RMS, elemental analysis and single-crystal X-ray diffraction. The crystal belongs space group P1 with a = 7.8772 (17), b = 8.2986 (18), c = 15.392 (3) A,? = 93.360 (4),? = 94.609 (4),? = 93.584 ) °, C 18 H 22 N 6 O 3 S, M_r = 402.47, V = 998.9 (4) A~3, Z = 2, F (000) = 422, D_c = 1.335 g / cm~3, μ = 0.194 mm -1, the final bioassay results indicate that the target bio-compound has good fungicidal activity against Gibberlla nicotiancola in EC50 value and FOfsp .niveum in EC_ (95) value.