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中南和西南有五个城市(成都、武汉、重庆、长沙、贵阳)共八个实验室参加了第三届亚太组织相容性专题讨论会HLA分型研究。对385例健康汉族人作了HLA-A,-B,-C,-DR和-DQ抗原分型。由会议计算中心分析数据,计算出HLA抗原频率、基因频率、两位点单倍型频率及遗传距离等遗传参数。结果表明中国南方汉族群体的HLA分布具有相对同质性。
A total of eight laboratories from five cities (Chengdu, Wuhan, Chongqing, Changsha and Guiyang) in Central South and Southwest China participated in the HLA typing of the 3rd Asia-Pacific Organizational Symposium. HLA-A, -B, -C, -DR and -DQ antigens were genotyped in 385 healthy Han Chinese. Analysis of the data from the conference center to calculate the genetic parameters of HLA antigen frequency, gene frequency, haplotype frequency of two loci and genetic distance. The results show that HLA distribution in Han Chinese population in South China is relatively homogeneous.