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盐酸氯胍(百乐君)是治疗瘧疾的特效药,解放后不久,我国制药厂就开始生产了,所采用的合成途径,大致沿用1946年 Curd 和Rose 二氏所发表的方法,其过程用反应式表示如下:
The proguanil hydrochloride (dipyridamole) is a cure for malaria. Shortly after the liberation, the pharmaceutical factory in our country started production. The synthetic route used was roughly the method published by Curd and Rose II in 1946. The process The reaction is expressed as follows: