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慢性乙型肝炎及其病毒携带者细胞免疫功能明显低下。DNA疫苗可被体细胞摄取并表达相应抗原 ,激发出保护性免疫应答 ,包括特异性CTL应答及特异性抗体的产生〔1〕。IL 12是目前发现对体内免疫活性细胞诱导和调节作用最强、范围最广的细胞因子。我们将HBVDNA疫苗 (
Chronic hepatitis B and its virus carriers significantly lower immune function. DNA vaccines can be taken up by the somatic cells and express the corresponding antigen, provoke a protective immune response, including specific CTL response and the production of specific antibodies [1]. IL 12 is the strongest and most extensively found cytokine that is currently found to induce and regulate immune-competent cells in vivo. We will HBVDNA vaccine (