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目的探讨血清同型半胱氨酸(Hcy)值对妊娠期糖尿病预后的价值。方法分别选取妊娠中期糖尿病患者184例为观察组,同期健康孕妇200人为对照组,检测两组血清Hcy水平并进行相关性分析。结果观察组中63例随妊娠期增长发展为妊娠期糖尿病合并高血压,其妊娠中期血清Hcy值(9.8±2.1)μmol/L与健康组孕妇(5.7±1.2)μmol/L及妊娠期单纯糖尿病者(7.6±1.7)μmol/L比较,差异有统计学意义(P<0.05)。结论通过对妊娠中期糖尿病患者的Hcy值检测,可早期发现妊娠期糖尿病合并高血压。
Objective To investigate the value of serum homocysteine (Hcy) in the prognosis of gestational diabetes mellitus. Methods One hundred and seventy four pregnant women with gestational diabetes mellitus were selected as observation group and 200 healthy pregnant women as control group respectively. Serum Hcy level was measured and the correlation was analyzed. Results Sixty-three patients with gestational diabetes mellitus and hypertension developed in the observation group. The serum Hcy in the second trimester of pregnancy (9.8 ± 2.1) μmol / L and 5.7 ± 1.2 μmol / L of pregnant women in the second trimester of pregnancy were significantly higher than those in the simple diabetes mellitus (7.6 ± 1.7) μmol / L, the difference was statistically significant (P <0.05). Conclusions The detection of Hcy in the second trimester of pregnancy can detect gestational diabetes mellitus complicated with hypertension.