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目的:分析妊娠期糖尿病孕妇血脂、胰岛素、C肽的变化特点。方法:选择正常妊娠妇女45例(Ⅱ组)及妊娠期糖尿病妇女35例(Ⅲ组),分别于孕晚期(32~40周)采空腹血测定血脂(胆固醇、甘油三脂、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇)、胰岛素及C肽,并与健康未孕妇女40例(Ⅰ组)进行比较。结果:①Ⅱ组血脂水平明显高于I组(P<0.01),而Ⅲ组血脂水平明显高于Ⅱ组及Ⅰ组(P<0.01)。②Ⅱ组较Ⅰ组胰岛素明显升高(P<0.01),Ⅲ组明显高于Ⅱ组及Ⅰ组(P<0.01)。③Ⅲ组C肽值明显高于Ⅱ组及Ⅰ组。结论:妊娠糖尿病血脂水平、胰岛素水平、C肽值明显高于正常妊娠和非孕妇女。
Objective: To analyze the changes of serum lipid, insulin and C-peptide in pregnant women with gestational diabetes. Methods: Forty five pregnant women (group Ⅱ) and 35 pregnant women with gestational diabetes (group Ⅲ) were selected. The levels of serum lipids (cholesterol, triglyceride, high density lipoprotein Cholesterol, low density lipoprotein cholesterol), insulin and C peptide, and compared with 40 healthy women without pregnancy (group Ⅰ). Results: ① The levels of serum lipids in group Ⅱ were significantly higher than those in group Ⅰ (P <0.01), while those in group Ⅲ were significantly higher than those in groups Ⅱ and Ⅰ (P <0.01). ② The insulin level in group Ⅱ was significantly higher than that in group Ⅰ (P <0.01), and in group Ⅲ was significantly higher than that in group Ⅱ and Ⅰ (P <0.01). ③ group C peptide value was significantly higher than group Ⅱ and Ⅰ group. Conclusion: The levels of serum lipids, insulin and C-peptide in gestational diabetes mellitus were significantly higher than those in normal and non-pregnant women.