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目的 探讨慢性冠状动脉闭塞病变介入治疗后对患者左心室射血功能、室壁运动的影响。方法 83例慢性闭塞病变的患者[平均闭塞时间(4.6±11)个月]因心绞痛行介入治疗,其中支架置入率为74.7％。介入治疗前以及术后(6.9±2.2)个月行超声心动图检查。超声测定左心室射血分数,评价左室局部室壁运动。结果左心室射血分数由治疗前57.3％±14％提高至随诊时的63.4％±11％(P<0.01)。患者左心室室壁运动以及心绞痛在成功进行介入治疗后有明显改善。结论 介入治疗可使闭塞冠状动脉开放,从而明显提高左心室的射血功能,改善缺血心肌的室壁运动。
Objective To investigate the effect of left ventricular ejection function and ventricular wall motion in patients with chronic coronary artery occlusion after interventional therapy. Methods Eighty-three patients with chronic occlusive disease [mean time to occlusion (4.6 ± 11) months] were treated with angina pectoris. The stent placement rate was 74.7%. Echocardiography was performed before intervention and after (6.9 ± 2.2) months. Left ventricular ejection fraction was measured by ultrasound to evaluate left ventricular regional wall motion. Results Left ventricular ejection fraction increased from 57.3% ± 14% before treatment to 63.4% ± 11% at follow-up (P <0.01). Patients with left ventricular wall motion and angina significantly improved after successful intervention. Conclusion Interventional therapy can open the occluded coronary arteries and significantly improve left ventricular ejection function and improve myocardial wall motion in ischemic myocardium.