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[目的 ]阐明Ⅰ型变态反应与急性乙型肝炎关系 .[方法 ]将 42例急性乙型肝炎病人随机分为治疗组和对照组 ,并观察了联合抗过敏疗法对急性乙型肝炎的疗效 .[结果 ]治疗组行联合抗过敏疗法后血清内谷丙转氨酶和总胆红素均比治疗前明显降低 ,而对照组治疗前后无明显变化 ;治疗组谷丙转氨酶及总胆红素复常天数明显短于对照组 .[结论 ]联合抗过敏疗法对急性乙型肝炎疗效显著 ,从而间接证明了免疫球蛋白E及其介导的Ⅰ型变态反应在急性乙型肝炎发病机理中的致病作用 .
[Objective] To clarify the relationship between type Ⅰ allergy and acute hepatitis B. [Method] 42 patients with acute hepatitis B were randomly divided into treatment group and control group, and the curative effect of combined anti-allergy therapy on acute hepatitis B was observed. [Results] The serum alanine aminotransferase and total bilirubin in the treatment group were significantly lower than those before treatment, while the control group had no significant changes before and after treatment; the alanine aminotransferase and total bilirubin recovery days Was significantly shorter than that of the control group. [Conclusion] The combination anti-allergy therapy has a significant curative effect on acute hepatitis B, which indirectly proves the pathogenic role of immunoglobulin E and its type I allergic reactions in the pathogenesis of acute hepatitis B .