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目的 评价胶体染料试纸条试验 (DDIA )在血吸虫病大规模现场筛查中的效果与费用。方法 在江苏省 10个血吸虫病流行市中 ,对 5～ 6 5周岁居民采用整群轮查的形式进行 DDIA+粪孵查病 ,统计并比较不同地区 (各市 )和不同流行程度 (传播阻断、传播控制、尚未控制 )地区居民 DDIA的阳性检出率 ;再根据各地的工资水平和经济状况 ,计算出不同地区血防查病的总费用 ,分析皮试 +COPT+粪孵和 DDIA +粪孵查病程序中各种费用的构成情况 ,比较两种查病程序的人均免疫筛查费用和人均综合查病费用。结果 2 0 0 3年用 DDIA共筛查 3180 0 9人 ,查出阳性 5 771人 ,平均阳性检出率为 1.81% ,不同地区 (各市 )居民 DDIA阳性率在 0 .0 4 %～ 5 .75 %之间 ;传播阻断、传播控制和尚未控制 3类地区 DDIA方法的居民阳性检出率分别为 0 .4 0 %、2 .6 6 %、4 .74 %。 DDIA程序的人均筛查费用和人均综合查病费用分别为 4 .4 2元和 4 .96元 ,分别比 COPT程序节省了 0 .92元和 0 .6 0元 ,所需人均费用分别减少了 17.2 3%和 10 .79% ,节省的费用主要来源于实验操作人工费。结论 利用 DDIA程序进行大规模综合查病时 ,血检阳性率比 COPT高 1倍 ,人均查病费用比 COPT程序节省10 %。
Objective To evaluate the efficacy and cost of the colloidal dye strip test (DDIA) in large-scale screening of schistosomiasis. Methods In the epidemic of 10 schistosomiasis cases in Jiangsu Province, residents of 5 ~ 65 years old were enrolled in the study of DDIA + stool hatching disease by means of cluster surveys. Statistics were carried out to compare the prevalence of different epidemics among different regions (cities) Spread control, not yet controlled) the positive rate of detection of DDIA in local residents; then calculate the total cost of blood tests and disease prevention in different areas according to the wage level and economic status of all regions; analyze skin test + COPT + manure hatching and DDIA + manure hatching disease The composition of the various costs of the program, comparing the two screening procedures per capita immune screening costs and per capita comprehensive disease costs. Results A total of 3180 0 9 people were screened by DDIA in 2003, with 5 771 positives detected. The average positive rate was 1.81%. The positive rate of DDIA among residents in different regions (cities) was 0. 04% ~ 5. 75%. The positive detection rate of residents with DDIA method in transmission block, transmission control and non-control of the three types of areas was 0.4%, 2.6%, 4.74% respectively. DDIA program per capita screening costs and per capita comprehensive examination costs were 4.42 yuan and 4.96 yuan, respectively, than the COPT program saved 0.92 yuan and 0.60 yuan, the required per capita costs were reduced 17.2 3% and 10 .79%, the cost savings mainly from laboratory labor costs. Conclusion The DDIA program for large-scale comprehensive disease detection, blood test positive rate 1 times higher than the COPT, per capita disease cost savings of 10% compared with the COPT program.