每天给小鼠0.2 mg 锌灌胃,连续15d,明显提高外周血 T 淋巴细胞百分率,促进 T淋巴细胞转化功能及迟发型超敏反应;对腹腔巨噬细胞吞噬功能有抑制作用、对 IgM 抗体生成及胸腺重量无明显影响。胸腺组织结构在光镜下未见明显变化,但在电镜下可见皮质淋巴细胞核形态有不规则变形。这些结果表明:一定剂量的锌对细胞免疫虽有促进作用,但对巨噬细胞吞噬功能有抑制作用,对胸腺淋巴细胞有潜在的损伤。 Mice fed 0.2 mg zinc daily for 15 days continuously increased the percentage of T lymphocytes in peripheral blood, promoted T lymphocyte transformation and delayed-type hypersensitivity, inhibited the phagocytosis of peritoneal macrophages and inhibited IgM antibody production And thymus weight no significant effect. Thymus tissue structure in the light microscope, no significant change, but in the electron microscope shows cortical lymphocyte nuclear irregular deformation. These results show that: a certain dose of zinc can promote cellular immunity, but macrophage phagocytosis was inhibited, the potential damage to the thymus lymphocytes.