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目的:通过体外试验研究土贝母鲜品脂溶性提取物的抗肿瘤活性。方法:采用薄层色谱法对该提取物进行成分分析,并对该提取物进行体外抗乳腺癌活性测试。结果:脂溶性成分主要为甾醇类化合物,且对4种乳腺癌细胞均有细胞毒作用。结论:为鲜土贝母开发研究提供数据参考。
OBJECTIVE: To study the antitumor activity of liposoluble extracts from fresh Fritillaria species in vitro. Methods: The constituents of this extract were analyzed by TLC, and the extract was tested for its anti-breast cancer activity in vitro. Results: The liposoluble components were mainly sterols and had cytotoxic effect on all four kinds of breast cancer cells. Conclusion: It provides data reference for the development and research of Fritillaria.