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目的:比较早发型与晚发型重度子痫前期(PE)患者的心脏损伤情况。方法:选取2012年4月至2014年5月在我院产科住院分娩的早发型及晚发型重度PE孕妇各50例,检测静脉血中心肌肌钙蛋白、心肌酶谱、脑钠肽前体含量,同时行心脏彩色多普勒超声检查。判定重度PE患者是否存在心脏损伤,并比较早发型与晚发型重度PE患者的心脏损伤程度的差异。结果:早发型及晚发型的重度PE孕妇的产前各项指标异常率均明显高于同期正常妊娠组,差异有统计学意义(P<0.05),但两种类型重度PE之间比较差异无统计学意义(P>0.05);两种类型产后各项指标均基本正常,差异无统计学意义(P>0.05)。结论:两种类型重度PE明显增加孕妇心脏损害的概率。早发型及晚发型患者产前心脏损害为可逆性。联合运用多种检测手段可早期发现重度PE患者心脏损害。
Objective: To compare the cardiac injury of early-onset and late-onset severe preeclampsia (PE) patients. Methods: From April 2012 to May 2014, 50 cases of early-onset and late-onset severe PE pregnant women who were hospitalized in obstetrics and gynecology hospital from April 2012 to April 2014 were enrolled in this study. Serum cardiac troponin, myocardial enzymes, , While undergoing cardiac color Doppler ultrasound. Determine the presence of heart failure in patients with severe PE, and compare the degree of heart damage in patients with early-onset and late-onset severe PE. Results: The rate of prenatal abnormalities in early-onset and late-onset severe PE pregnant women was significantly higher than that in normal pregnancy (P <0.05), but there was no significant difference between the two types of severe PE Statistical significance (P> 0.05); The two types of postpartum indicators were normal, the difference was not statistically significant (P> 0.05). Conclusions: Both types of severe PE significantly increase the probability of heart damage in pregnant women. Early onset and late onset patients with prenatal heart damage reversible. Combined use of multiple detection methods can be early detection of heart failure in patients with severe PE.