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目的:探讨参麦注射液联合强化康复治疗对缺血性中风恢复期患者血清hs-CRP、血脂水平及临床疗效。方法:选择医院缺血性中风恢复期患者84例,按随机数字表法分组,对照组42例予强化康复训练。研究组42例予强化康复训练联合参麦注射液,治疗前后比较血清IL-6、IL-1β、hs-CRP水平,测定生活能力、综合康复能力及运动、感觉恢复状况,对比临床疗效。结果:在临床疗效及运动感觉恢复上,研究组有效率(92.86%、90.48%、90.48%)均优于对照组(78.57%、66.67%、69.04%),具有统计学意义(P<0.05);研究组治疗后血清CRP、IL-6及IL-1β低于对照组,研究组治疗后综合康复能力、日常生活能力均高于对照组,NIHSS评分低于对照组(P<0.05),两组血脂无变化。结论:采用参麦注射液联合强化康复训练能降低缺血性中风恢复期患者hsCRP水平,对血脂无影响,效果显著。
Objective: To investigate the effect of Shenmai injection combined with intensive rehabilitation on serum hs-CRP, blood lipid level and clinical efficacy in patients with ischemic stroke recovery. Methods: Eighty-four patients with ischemic stroke during hospitalization were selected and randomly divided into two groups. Forty-two patients in control group were given intensive rehabilitation training. 42 cases in the study group were given intensive rehabilitation training combined with Shenmai injection. Serum levels of IL-6, IL-1β and hs-CRP were compared before and after treatment. The viability, comprehensive rehabilitation ability, motor and sensory recovery were compared before and after treatment. Results: The effective rate (92.86%, 90.48%, 90.48%) in the study group was significantly higher than that in the control group (78.57%, 66.67%, 69.04%) in the clinical efficacy and motor sensory recovery, with statistical significance (P0.05) . The levels of CRP, IL-6 and IL-1β in the study group were lower than those in the control group. The study group’s comprehensive rehabilitation ability and daily living ability were higher than those in the control group, NIHSS score was lower than the control group (P <0.05) No changes in blood lipids. Conclusion: The combination of Shenmai injection and intensive rehabilitation training can reduce hsCRP levels in patients with ischemic stroke during recovery and have no effect on blood lipids, with a significant effect.