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目的探讨妊娠期糖尿病产妇血清中糖化血红蛋白和白蛋白水平与妊娠期糖尿病患者术后感染风险及医疗费用的关系。方法选取本院2013年1月-2016年1月确诊为妊娠期糖尿病的患者120例,研究患者血清中糖化血红蛋白和白蛋白水平与妊娠期糖尿病患者术后感染风险及医疗费用的关系,并采用Logistic回归探讨患者妊娠期糖尿病产后感染的风险因素。结果 ALB高水平组患者GLU、2 h PG、HOMA-IR、Hb A1C水平均低于对应ALB低水平组;高水平的ALB、Hb A1C患者住院时间、护理费、治疗费、总费用均低于相应低水平组;低水平的ALB患者切口感染、尿路感染、肺部感染、其他感染的发病率高于高水平组的患者,而低水平的Hb A1C患者切口感染、尿路感染、肺部感染、其他感染的发病率低于高水平组患者,上述差异均有统计学意义(P<0.05)。Logistic回归分析结果提示血清中ALB(P<0.05)、Hb A1c(P=0.05)是妊娠期糖尿病的产后感染的独立风险因素。结论妊娠糖尿病患者血清白蛋白和糖化血红蛋白水平与患者妊娠预后密切相关。
Objective To investigate the relationship between the serum glycoprotein and albumin levels in gestational diabetes mellitus and the risk of postoperative infection and the medical cost in gestational diabetes mellitus. Methods A total of 120 patients with gestational diabetes mellitus diagnosed in our hospital from January 2013 to January 2016 were enrolled in this study. The relationship between serum glycated hemoglobin and albumin level and the risk of postoperative infection and medical expenses in gestational diabetes mellitus were studied. Logistic regression analysis of risk factors for postpartum infection in gestational diabetes in patients. Results The levels of GLU, 2 h PG, HOMA-IR and Hb A1C in patients with high ALB level were lower than those in patients with low ALB level. The hospitalization time, nursing fees, treatment costs and total costs were lower in patients with high ALB and Hb A1C Correspondingly low level group. Incision infection, urinary tract infection and lung infection in ALB patients with low level were higher than those in high level group, while patients with low level Hb A1C incision infection, urinary tract infection, lung Infection, the incidence of other infections were lower than the high-level patients, the above differences were statistically significant (P <0.05). Logistic regression analysis showed that serum ALB (P <0.05) and Hb A1c (P = 0.05) were independent risk factors for postpartum infection in gestational diabetes mellitus. Conclusion The serum albumin and HbA1c of patients with gestational diabetes are closely related to the prognosis of pregnancy.