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Nanoarchitectonics provide versatile opportunities for modifying the properties of coordination polymers (CP) other than molecular engineering.Spatial-controlled etching focuses on the controlled disassembly of the frameworks.The etching method provides an excellent opportunity for tailoring the properties and functions of the CPs.Here,we discuss the mechanism for controlled etching of the CPs and summarized the two main strategies utilized so far.Several examples are illustrated to demonstrate recent developments in this area.Moreover,advantages of the etched CPs are summarized in several important applications,including energy storage,catalysis and nanomedicine.