论文部分内容阅读
本文报告1例使用紫杉特尔(docetaxel,taxotere)治疗的肺癌患者由腐败性梭菌而引发盲肠炎和败血症死亡。 患者男性,46岁。因下腹疼痛、发热及呕吐8小时入院,8个月前诊断为局部晚期鳞状细胞癌,并给予顺氯氨铂及长春碱治疗。治疗后2个月输注紫杉特尔200mg/m~2;口服甲基泼尼松龙24mg,每日2次,共4天。治疗后5天,患者出现暂时的红斑丘疹、关节痛、肌痛及无力。入院时有轻度类似腹膜炎症状。血白细胞计
This article reports a case of lung cancer patients treated with docetaxel (taxotere) that caused caecal and sepsis deaths from spoilage Clostridium. The patient is 46 years old. Eight hours after hospitalization for abdominal pain, fever, and vomiting, a diagnosis of locally advanced squamous cell carcinoma was performed 8 months earlier. She was treated with cisplatin and vinblastine. After 2 months of treatment, taxane 200 mg/m~2 was infused; methylprednisolone 24 mg was administered twice a day for 4 days. Five days after treatment, the patient experienced temporary erythematous papules, joint pain, myalgia, and weakness. Mild peritonitis symptoms on admission. Blood white cell count