目的评价控制危险因素达标与强化他汀治疗对动脉粥样硬化的影响。方法选择我院超声检查发现颈动脉内中膜厚度（ IMT）>1mm的患者112例，随机分为两组，分别给予控制危险因素达标及强化他汀治疗，疗程12月，再用彩超测定颈动脉IMT，并计算斑块积分。结果两组血压、血糖及血脂均达标，A组LDL-C下降了15%，而B组LDL-C则下降52%，彩超结果显示A组中颈动脉 IMT及斑块积分与治疗前相比增大，但差异无统计学意义（P>0.05），而B组则明显减小，差异显著（P1mm were enrolled, who were examined by Carotid ultrasonograph.They were randomly divided into two groups, group (A) were administered with treating risk factor, group (B)were given atorvastatin 80mg once daily, furthermore,12 months later they were scanned again by Carotid ultrasonograph. Results The Carotid IMT and plaque score in group A increased , however the difference did not reach statistical significance Compared with the data before treatment (P>0.05), whereas , those in group B decreased greatly (P<0.05).Conclusion Treating risk factor only can not prevent the progression of atherosclerosis effectively ,instead,strengthening atorvastatin therapy can do.