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目的:探究2016—2018年北京市通州区手足口病流行病学特征,为手足口病的防控和预测工作提供数据支持。方法:收集“中国疾病预防控制信息系统”报告的通州区2016—2018年上报的手足口病病例资料,进行描述性流行病学分析，运用简单季节性模型预测通州区2019年发病趋势。结果:2016—2018年通州区总计报告手足口病8 877例，其中重症病例13例，无死亡病例。6—8月是发病主要高峰,城乡结合部总体发病率高于农村和中心城区。男性发病数多于女性，性别比为1.44：1。发病年龄主要集中在5岁及以下儿童，以1~3岁为主。人群分布主要集中在散居和托幼儿童。结论:北京市通州区手足口病发病呈现出明显的季节性和地区性差异。五岁以下散居儿童为防控的重点，应根据流行病学特征以及预测的发病趋势，有针对性的做好防控工作。“,”Objective:To explore the epidemiological characteristics of hand, foot, and mouth disease (HFMD) in Tongzhou district of Beijing from 2016 to 2018, so as to provide reliable scientific evidence for the prevention and control of HFMD.Methods:Descriptive epidemiological analysis was used to analyze the incidence surveillance data of HFMD cases in Tongzhou district of Beijing reported in the “Chinese Disease Prevention and Control Information System” from 2016 to 2018. Simple seasonal model was applied to predict the incidence trend of HFMD in Tongzhou district in 2019.Results:A total of 8 877 HFMD cases were reported in Tongzhou district during 2016 to 2018, including 13 severe cases and no death case. The main incidence peak occurred from June to August. The overall incidence rate of urban-rural continuum was higher than those of rural and central urban areas. The number of male cases was higher than that of females cases and the ratio was 1.44 : 1. Most of the cases were children under 5 years old, mainly children of 1-3 years old. Scattered and kindergarten children were the main groups.Conclusion:The obvious seasonal and regional differences of HFMD were observed in Tongzhou district of Beijing. The scattered children under 5 years old should be focused for HFMD prevention and control. Targeted work of prevention and control should be carried out according to the epidemiological characteristics and predicted incidence trend.