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目的:探讨复方麻黄碱滴鼻液浑浊的原因。方法:将处方中各成分两两分组配伍,对滤过前后溶液的抑菌圈及含量进行比较。结果:苯扎溴铵与地塞米松磷酸钠配伍产生浑浊,并且滤过液的抑菌圈和地塞米松磷酸钠的含量均明显小于原液。结论:复方麻黄碱滴鼻液配制过程中出现浑浊是由于苯扎溴铵与地塞米松磷酸钠部分发生反应所致。
Objective: To investigate the reason of compound ephedrine nasal opacity. Methods: The ingredients of the prescription two by two compatibility, before and after the filtrate inhibition zone and content were compared. Results: The combination of benzalkonium bromide and dexamethasone sodium phosphate produced turbidity, and the contents of inhibition zone and dexamethasone sodium phosphate in the filtrate were significantly lower than those of the original solution. Conclusion: The ophthalmological ephedrine nasal drops during the preparation of turbidity is due to the reaction between benzalkonium bromide and dexamethasone sodium phosphate.