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目的:测定妊娠糖尿病(GDM)孕妇血铬含量及其临床意义。方法:61例GDM孕妇为研究对象,糖耐量正常孕妇37例为对照组,测定两组血清铬含量、空腹血糖(FBG)和空腹胰岛素(FINS)。结果:GDM孕妇血铬含量明显低于正常孕妇(P<0.05),FBG、FINS和胰岛素敏感指数(ISI)均高于正常孕妇(P<0.05),GDM组血清铬与ISI、FBG、FINS均呈负相关,其中血清铬与ISI相关性最强。结论:GDM孕妇存在着明显的铬缺乏,补充适量的铬有助于改善胰岛素抵抗。
Objective: To determine the blood chromium level in pregnant women with gestational diabetes mellitus (GDM) and its clinical significance. Methods: Totally 61 pregnant women with GDM were enrolled in this study. Totally 37 pregnant women with normal glucose tolerance were used as control group. Serum chromium, fasting blood glucose (FBG) and fasting insulin (FINS) were measured in both groups. Results: The levels of blood chromium in GDM pregnant women were significantly lower than those in normal pregnant women (P <0.05), FBG, FINS and insulin sensitivity index (ISI) were higher than those in normal pregnant women (P <0.05) Was negatively correlated, with the strongest correlation between serum chromium and ISI. CONCLUSIONS: There is a clear chromium deficiency in GDM pregnant women. Supplementation of adequate chromium helps to improve insulin resistance.