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目的 观察快速脱敏疗法治疗儿童变应性哮喘的近期疗效。方法 将 45例哮喘患儿随机分为快速脱敏组 (A组 ) 2 4例和常规脱敏组 (B组 ) 2 1例 ,选用皮试阳性反应最明显的一种为脱敏变应原进行脱敏治疗。全部患儿在治疗前及治疗 6个月后进行气道反应性和肺功能测定。结果 A组总有效率为 83.33% ,B组为 46 .72 %。两组疗效比较有显著性差异 (P <0 .0 5 )。两组治疗后气道反应性和肺功能结果比较差异有显著性 (P <0 .0 5 )。结论 快速脱敏疗法治疗儿童变应性哮喘的近期疗效、气道反应性的降低和肺功能的改善均优于常规脱敏法 ,更能尽快控制哮喘发作。
Objective To observe the short-term curative effect of rapid desensitization therapy in children with allergic asthma. Methods Forty-five children with asthma were randomly divided into 24 cases of rapid desensitization group (A group) and 21 cases of conventional desensitization group (Group B). One of the most obvious positive reactions of skin test was desensitization allergen Desensitization treatment. All children before treatment and after 6 months of treatment for airway reactivity and pulmonary function tests. Results The total effective rate was 83.33% in group A and 46.72% in group B. There was significant difference between the two groups (P <0.05). There was significant difference in airway reactivity and pulmonary function between the two groups after treatment (P <0.05). Conclusion The rapid desensitization therapy for children with allergic asthma short-term efficacy, decreased airway responsiveness and pulmonary function are better than the conventional desensitization method, but also to control asthma attacks as soon as possible.