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以干细胞为种子细胞构建组织工程化皮肤成为当前研究的热点之一。皮肤干细胞主要有表皮干细胞和毛囊干细胞。毛囊干细胞在体内表现为慢周期性,在体外培养时具有高克隆形成能力,毛囊干细胞作为组织工程化皮肤的新种子细胞受到关注。
The construction of tissue-engineered skin stem cells as seed cells has become one of the hot topics in current research. Skin stem cells are mainly epidermal stem cells and hair follicle stem cells. Hair follicle stem cells show slow cycle in vivo and have high clonogenic capacity when cultured in vitro. Hair follicle stem cells are attracting attention as new seed cells of tissue-engineered skin.