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目的:探讨马来酸曲美布汀胶囊在肠易激综合症治疗中的应用效果及临床意义。方法:选取经我院临床确诊为肠易激综合症的患者48例为观察研究对象,依据临床治疗方法的不同分为观察组和对照组各24例,对两组疗效进行对比分析,指导临床用药诊治实践。结果:两组进行12周治疗后,联用马来酸曲美布汀胶囊治疗组的患者在临床症状改善、HAMD评分等方面均好于对照组,两组差异性有统计学意义(P<0.05)。结论:马来酸曲美布汀胶囊治疗肠易激综合症疗效确切,可明显改善患者临床症状,提高治愈效果,具有积极的临床价值
Objective: To investigate the effect and clinical significance of trimebutine maleate capsule in the treatment of irritable bowel syndrome. Methods: Forty-eight patients diagnosed as irritable bowel syndrome (IBS) in our hospital were selected as observational subjects. According to the different clinical treatment methods, 24 cases were divided into observation group and control group respectively. The curative effect was compared between the two groups to guide clinical Medication practice. Results: After treatment for 12 weeks in both groups, the patients treated with trimebutine maleate in the treatment group were better than the control group in clinical symptoms improvement and HAMD score, the difference was statistically significant (P < 0.05). Conclusion: Trimebutine maleate capsule for the treatment of irritable bowel syndrome is effective, can significantly improve the clinical symptoms and improve the cure effect, with a positive clinical value