目的探讨米非司酮配伍索前列醇中期引产的临床效果。方法回顾性分析我院妇产科对126例孕16~24周要求终止妊娠的患者临床资料。结果应用米非司酮配伍索前列醇中期引产,患者痛苦少,副反应少,出血量少,完全流产率高,无子宫破裂、羊水栓塞、过敏性休克及感染并发症。结论米非司酮配伍索前列醇终止中期妊娠的效果明显优于其它药物引产,具有安全、简便、成功率高的特点,值得推广使用。 Objective To investigate the clinical effect of mifepristone combined with midoprazole in mid-term induction of labor. Methods A retrospective analysis of obstetrics and gynecology in our hospital of 126 cases of pregnancy 16-24 weeks required termination of pregnancy clinical data. Results Mifepristone compatibility with midoprazole mid-term labor, patients with less pain, fewer side effects, less bleeding, high total abortion rate, no uterine rupture, amniotic fluid embolism, anaphylactic shock and complications of infection. Conclusion The efficacy of mifepristone combined with somatropin termination of midterm pregnancy is significantly better than that of other drugs. It is safe, simple and has a high success rate. It is worth promoting.