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目的旨在探讨善宁治疗急性胰腺炎的疗效。方法将144例急性胰腺炎随机分成对照组、治疗组,治疗组在对照组治疗方案基础上加用善宁0.2mg静脉滴注,每8小时一次。结果治疗组总有效率为94.44%,对照组总有效率为72.22%,疗效明显优于对照组。结论善宁对多种外源性与内源性刺激引起的胰腺外分泌具有明显抑制作用,还能有效抑制胆囊收缩素、胰泌素的分泌,松弛oddi括约肌有利于胰管引流,用于急性胰腺炎的治疗,在阻止病情发展、稳定病情、缩短疗程、减少远期并发症等方面较常规用药都具有十分显著的优越性。
The purpose is to explore the effect of Shanning in the treatment of acute pancreatitis. Methods 144 cases of acute pancreatitis were randomly divided into control group, treatment group and treatment group in the control group on the basis of the treatment plan plus Shanning 0.2mg intravenous infusion, once every 8 hours. Results The total effective rate of the treatment group was 94.44%, the total effective rate of the control group was 72.22%, the efficacy was significantly better than the control group. Conclusions Shanning can significantly inhibit pancreatic exocrine secretion induced by many exogenous and endogenous stimuli, but also effectively inhibit the secretion of cholecystokinin and secretin. Relaxing oddi sphincter facilitates the pancreatic duct drainage for acute pancreas The treatment of inflammation has a very significant superiority in stopping the progression of the disease, stabilizing the condition, shortening the course of treatment, reducing the long-term complications and the like, compared with the conventional medicine.