新交感酚(neosynephrine)为拟交感神经药物,主要作用于α-受体,眼科广用于扩瞳,通常用浓度为10%的溶液。但平时使用比较随便,甚或滥用。有者一次数滴,而致吸收引起全身毒性副作用。近年报告中毒病例已逾30。另有介绍电子显微镜检查,见使用新交感酚的角膜内皮细胞呈现局部毒性反应。故Frauenfelder等(1978)首先提出几项使用原则,如规定一小时内仅滴一次,不用于老年人(改用2.5%溶液)。本文研究2.5%及10%新交感酚(用量均为一滴)的诊断性扩瞳作用。其观察11～76岁30人(均试验一眼),无特殊眼病,泪道正常。每例共试验2次,间隔2天。每次约滴溶液量为40 Neosynephrine is a sympathomimetic drug that acts mainly on the alpha-receptor and is widely used in dilation of the pupils, usually at a concentration of 10%. But usually more casual, or even abuse. One of the few drops, which caused systemic side effects caused by absorption. In recent years, more than 30 cases of poisoning have been reported. Another introduction of electron microscopy, see the use of new Syrian phenol corneal endothelial cells showed partial toxicity. Therefore, Frauenfelder et al. (1978) first proposed several principles of use, such as providing only one drop per hour and not for the elderly (using 2.5% solution). This article studies 2.5% and 10% neogestrel (dosage is a drop) diagnostic dilation effect. The observation of 11 to 76 years old 30 (both test one), no special eye disease, normal lacrimal duct. Each case a total of 2 tests, an interval of 2 days. Each drop of solution is about 40