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患者,女,25岁.因腹部不适晚饭后口服先锋霉素Ⅳ0.25g,夜间觉口腔不适,口腔粘膜出现红色丘疹及大小不等水疱,之后迅速漫延至整个口腔及唇红,局部出现严重糜烂、溃疡,疼痛严重,影响睡眠.追问病史,患者先日晚觉腹部不适,口服两粒先锋霉素Ⅳ未同时服用其它药物.口腔检查:口腔粘膜尚有散丘性紫色丘疹,双颊、硬腭、软腭、悬雍垂、咽侧壁、唇红、口角有大小不等的水疱、糜烂面及溃疡,表面有血性分泌物及黄色假膜,舌大片乳头上皮剥脱、颌下、颏下淋巴结肿大,皮肤及身体其他部位无类似损害.口腔病损分泌物徐片镜检及细菌培养未发现病原菌.
Patients, female, 25. Suffering from abdominal discomfort after oral administration of cephalosporin IV0.25g, nighttime mouth discomfort, oral mucosa, red papules and sizes ranging from blisters, and then quickly spread to the entire oral cavity and lip red, local severe erosion , Ulcer, severe pain, affecting sleep.Question history, the patient feel abdominal discomfort the first day and night, oral administration of two cephalosporin IV did not take other drugs at the same time.Oral examination: there are scattered oral mucosa purple papules, cheeks, hard palate, Soft palate, uvula, pharyngeal side wall, lip red, mouth has varying sizes of blisters, erosion and ulcers, bloody discharge on the surface and the yellow pseudomembranous, tongue large papillary epithelium exfoliation, submandibular and submental lymph nodes , Skin and other parts of the body without any similar damage Oral lesions secretions Xu microscopic examination and bacterial culture found no pathogens.