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目的探讨应用阿莫西林、卡孕栓、阿托品、地西泮、利多卡因序贯治疗(A-M-A-D-L方案)在负压吸引人流术中的临床价值。方法选择2011年8月至2013年8月驻马店市第一人民医院妇产科收治的需行人工流产的妇女114例,根据应用药物的不同随机分为研究组(55例)和对照组(59例),研究组应用阿莫西林、卡孕栓、阿托品、地西泮、利多卡因序贯治疗方案(A-M-A-D-L方案),对照组应用芬太尼及异丙酚静脉镇痛麻醉无痛人流。结果研究组镇痛有效率为96.43%,对照组为98.31%,两组效果对比差异无统计学意义(P>0.05);研究组宫颈松驰有效率为96.36%,显著优于对照组的72.88%,差异有统计学意义(P<0.05)。研究组手术用时、术中出血量、术后子宫出血停止时间等显著低于对照组,差异有统计学意义(P<0.05)。结论 A-M-A-D-L方案在配合负压吸引人工流产术终止早期妊娠中有良好的应用价值。
Objective To investigate the clinical value of amoxicillin, carbamazepine, atropine, diazepam, lidocaine sequential therapy (A-M-A-D-L regimen) Methods A total of 114 women admitted to the Department of Obstetrics and Gynecology of First People’s Hospital of Zhumadian City from August 2011 to August 2013 were randomly divided into study group (55 cases) and control group (59 cases) In the study group, amoxicillin, carbamazepine, atropine, diazepam and lidocaine sequential therapy (AMADL regimen) were used in the study group. The control group was given analgesia with fentanyl and propofol for painless anesthesia. Results The analgesic effective rate was 96.43% in the study group and 98.31% in the control group. There was no significant difference between the two groups (P> 0.05). The effective rate of cervical relaxation in the study group was 96.36%, which was significantly better than that of the control group %, The difference was statistically significant (P <0.05). The operation time, intraoperative blood loss, postoperative uterine bleeding stop time were significantly lower in the study group than in the control group (P <0.05). Conclusion The A-M-A-D-L regimen has good application value in the termination of early pregnancy with vacuum induced abortion.