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目的探讨血栓弹力图检测对急性脑梗死患者阿司匹林疗效的监测作用。方法对60例口服阿司匹林的急性脑梗死患者分别进行光学法血小板聚集率和血栓弹力图检测,比较2种检测方法的结果。结果血小板聚集率和血栓弹力图检测血小板抵抗有较好的一致性(Kappa=0.76)。结论血栓弹力图检测对服用阿司匹林的急性脑梗死患者的药物疗效有较高临床价值,可用于评价抗血小板药物的临床疗效,指导临床治疗。
Objective To investigate the monitoring effect of thromboelastography on aspirin in patients with acute cerebral infarction. Methods Sixty patients with acute cerebral infarction who were taking aspirin were respectively examined by optical platelet aggregation rate and thrombus elasticity test. The results of two methods were compared. Results Platelet aggregation and thrombus elastography showed good agreement with platelet resistance (Kappa = 0.76). Conclusion The test of thrombi elastography has high clinical value in the treatment of acute cerebral infarction patients taking aspirin. It can be used to evaluate the clinical efficacy of antiplatelet drugs and guide the clinical treatment.