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研究口服果糖二磷酸钠（ＦＤＰ）对动物缺氧及急性脑缺血的作用。方法：采用密闭、断头、结扎双侧带迷走神经颈总动脉等方法，观察ＦＤＰ对缺氧及急性脑缺血小鼠的影响；采用结扎双侧颈总动脉的方法，观察ＦＤＰ对急性脑缺血大鼠的影响。结果：ＦＤＰ可显著延长密闭、断头、结扎双侧带迷走神经颈总动脉后小鼠的死亡时间；可明显抑制结扎双侧颈总动脉大鼠的脑指数、脑含水量和血清磷酸肌酸激酶的增高，对脑血管通透性和血清乳酸脱氢酶的增高有抑制趋势，但作用不明显。结论：口服ＦＤＰ对动物缺氧及急性脑缺血有保护作用。
To study the effect of oral administration of fructose diphosphate (FDP) on hypoxia and acute cerebral ischemia in animals. Methods: Anesthesia, decapitation and ligation of bilateral common vagus nerve common carotid arteries were used to observe the effect of FDP on hypoxia and acute cerebral ischemia in mice. The bilateral common carotid arteries were ligated to observe the effect of FDP on acute cerebral ischemia Effects of blood on rats. Results: FDP can significantly prolong the time of death of the common carotid arteries in the bilateral common carotid arteries after occlusion, decapitation and ligation, and significantly inhibit the brain index, brain water content and serum creatine phosphokinase Of the increase of cerebral vascular permeability and serum lactate dehydrogenase increased inhibitory trend, but the effect is not obvious. Conclusion: Oral FDP can protect animals from hypoxia and acute cerebral ischemia.