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１９９４年１～５月对北京地区１３４例急性呼吸系统疾病患者，以及与此配对的１３４例因其他疾病就诊的患者进行了前瞻性肺炎衣原体感染的研究。采用微量荧光试验检测肺炎衣原体ＩｇＧ抗体，其阳性率分别为９３％和８９％（Ｐ＞０．１）。两者患者抗体几何均数差异也未见有显著性（５５．９±４．２对４１．７±２．８，Ｐ＞０．１）。４例（４／３０）肺炎和６例（６／８１）支气管炎患者血清学诊断为近期肺炎衣原体感染。慢性支气管炎病史在肺炎衣原体感染者的伴随频率显著高于非肺炎衣原体感染者（Ｐ＜０．０５）。肺炎衣原体ＩｇＧ抗体几何滴度在具有慢性支气管炎患者中显著高于无该病史患者（Ｐ＜０．０５）。１３４例研究组患者咽后壁拭子肺炎衣原体分离全部为阴性。
From January to May 1994, 134 patients with acute respiratory diseases in Beijing and 134 matched patients with other diseases were enrolled in this study. The detection rate of Chlamydia pneumoniae IgG antibody by micro fluorescence assay was 93% and 89%, respectively (P> 0.1). There was also no significant difference in geometric mean between the two patients (55.9 ± 4.2 vs. 41.7 ± 2.8, P> 0.1). Four (4/30) pneumonia and 6 (6/81) bronchitis patients were serologically diagnosed as Chlamydia pneumoniae infection. The history of chronic bronchitis was significantly higher in Chlamydia pneumoniae patients than in non-Chlamydia pneumoniae patients (P <0.05). The geometric titers of IgG antibodies to Chlamydia pneumoniae in patients with chronic bronchitis were significantly higher than those without this history (P <0.05). 134 cases of study group patients with retropharyngeal swab pneumoniae chlamydia separation were all negative.