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目的研究坦索罗辛联合黄体酮穴位注射治疗输尿管下段结石的临床疗效。方法将2016年1月~2017年1月对我院收治的80例输尿管下段结石患者随机分为两组,每组40例。对照组仅予坦索罗辛缓释片;观察组采用坦索罗辛联合黄体酮穴位注射法。对比分析两组的结石排除率、排出时间、肾绞痛发生情况、疼痛缓解时间、治疗效果和并发症等的差异。结果观察组的治疗有效率为95%,明显高于对照组的80%,差异具有统计学意义(P<0.05)。观察组的结石排除率为87.5%,明显高于对照组的67.5%,差异具有统计学意义(P<0.05)。观察组的结石排出时间、肾绞痛发生率和疼痛缓解时间显著低于对照组,差异具有统计学意义(P<0.05)。观察组的并发症发生情况与对照组差异无统计学意义(P>0.05)。结论坦索罗辛联合黄体酮穴位注射治疗输尿管下段结石疗效显著,在临床中值得推广应用。
Objective To study the clinical efficacy of tamsulosin combined with progesterone injection in the treatment of lower ureteral calculi. Methods From January 2016 to January 2017, 80 patients with lower ureteral calculi admitted to our hospital were randomly divided into two groups, 40 cases in each group. The control group only tamsulosin sustained release tablets; observation group tamsulosin combined progesterone injection. The differences of the rate of stone removal, the time of discharge, the occurrence of renal colic, the pain relief time, the curative effect and complication were compared between the two groups. Results The effective rate of treatment in the observation group was 95%, which was significantly higher than that in the control group (80%), the difference was statistically significant (P <0.05). The stone removal rate in the observation group was 87.5%, which was significantly higher than that in the control group (67.5%), the difference was statistically significant (P <0.05). The observation group of stone discharge time, the incidence of renal colic and pain relief time was significantly lower than the control group, the difference was statistically significant (P <0.05). There was no significant difference between the observation group and the control group (P> 0.05). Conclusion Tamsulosin combined with progesterone acupuncture for the treatment of lower ureteral calculi significant effect, worth promoting in the clinical application.